What is a Biopsy?

A biopsy is a procedure to remove tissue or skin samples for laboratory examination. A doctor can use biopsies to diagnose including skin cancer, benign skin lesions, as well as other conditions. 

Indications for Biopsy 

A biopsy is indicated for the following: 

• Actinic keratosis 

• Bullous pemphigoid and other blistering skin disorders 

• Inflammatory skin conditions 

• Skin cancers, including basal cell carcinoma, squamous cell carcinoma and melanoma 

• Some skin infections 

• Skin tags 

• Suspicious moles or other growths 

• Warts 

A biopsy typically takes about 15 minutes 

Risks

Risks of a biopsy include:  

• bleeding  

• dehiscence 

• pain 

• scarring  

• infection  

• blood clot 

What to expect 

During the procedure 

You then receive a local anesthetic to numb the biopsy site. The numbing medication can cause a burning sensation in the skin for a few seconds. Afterward, you shouldn't feel any pain or discomfort during the skin biopsy.  

During a shave biopsy, your doctor uses a sharp tool, a double-edged razor or a scalpel to cut the tissue. The depth of the cut varies. A shave biopsy causes bleeding. Pressure and a topical medication might be applied to stop bleeding. 

During a punch biopsy or an excisional biopsy, your doctor cuts into the top layer of fat beneath the skin. Stitches may be needed to close the wound. A bandage is then placed over the wound to protect it and prevent bleeding. 

After the procedure 

Healing of the wound can take several weeks but is usually complete within two months. Wounds on the legs and feet tend to heal slower than those on other areas of the body. 

Results 

You will have a follow up appointment with your doctor to review the results of any samples taken during the biopsy.